![]() Moreover, the difference in wrapping efficiency between soft and rigid spherical NPs increases with their sizes, due to the increment of their elastic energy change. Under the volume constraint of elastic NPs, the soft spherical NPs are found to have similar contact edge lengths to rigid ones and to less efficiently be fully wrapped due to their elastic deformation. The thermodynamic driving force represents the amount of required free energy to drive NPs into a cell. The receptor diffusion kinetics refer to the kinetics of receptor recruitment that are affected by the contact edge length between the NP and membrane. Simulation results provide clear evidence that the membrane wrapping efficiency of NPs during endocytosis is a result of competition between receptor diffusion kinetics and thermodynamic driving force. Finish by twisting both ends of the tissue paper closed.Using coarse-grained molecular dynamics simulations, we systematically investigate the receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging from 25 to 100 nm, and shapes, including sphere-like, oblate-like, and prolate-like. Wrap the tissue paper along the round side of the present, then tape it shut. If you’re wrapping a cylindrical present, you’ll want to wrap the item in tissue paper instead of wrapping paper. Again, crease the edge to secure the fold. Then, push the bottom flap upward so it overlaps with the top flap. Next, push the top flap down and crease the edge to secure it. Use your fingers to crease each fold to secure it in place. ![]() You will notice four triangle shaped folds on each of the box's corners. Next, starting on one side, tuck in the paper on the corners of the box. Fold over the other side of the paper and tape it as well. Now, tape one side of the paper to the box. Cut a straight line across the upper layer of wrapping paper so it overlaps the bottom layer by a few inches or centimeters. The box should now be completely covered in wrapping paper. Then, roll the tube of the wrapping paper over the box all the way to the opposite end of the box. Take the edge of the wrapping paper and wrap it around the box so it covers about half the box. Place the item you are wrapping with the top facing down in the middle of the paper. ![]() To wrap something, first find a flat surface and unroll the wrapping paper so the white side is facing up. This article has been viewed 3,274,126 times. This article received 16 testimonials and 82% of readers who voted found it helpful, earning it our reader-approved status. WikiHow marks an article as reader-approved once it receives enough positive feedback. There are 8 references cited in this article, which can be found at the bottom of the page. is a creative hub that offers a wide range of workshops, tools, and resources for any craft project to inspire creativity and community engagement. She worked as a graphic designer before starting her own business. Amy holds a BS in Industrial Design from Philadelphia University. She offers monthly in-person and online workshops along with having developed a range of DIY craft kits for at-home projects. Amy specializes in macrame, DIY crafting, and teaching fiber arts. ![]() Amy Guerrero is an Arts and Crafts Specialist and the Owner of Sunshine Craft Co., a crafting studio based in Phoenix, Arizona. This article was co-authored by Amy Guerrero. ![]()
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